Even if the in the past-classified mutation try extinct, it may still be you are able to to make use of its before-determined chart updates once the an examination for the chance that it did lay in one locus once the freshly uncovered mutation. This is accomplished through the brand new alert so you can kiddies of one’s newly bare mutation together with a beneficial polymorphic DNA marker you to definitely maps close to the in past times-determined mutant chart reputation (approaches for identifying suitable DNA markers are chatted about in chapters 8).
